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106 JEFFERSON offers an exceptional experience rooted in the spirit of the community. This connection to Huntsville—with all its lofty aspirations and local charm—is what sets us apart from other hotels not only in design but hotel offerings. The look and feel of our hotel harkens back to the era of the space race that lifted this community to new heights and continues to inspire us today. Our goal is to bring this inspiration to our guests through the professionalism and attention to detail in our offerings combined with customer service that is genuine, warm, and welcoming.
Step into the mid-century charm of our exquisitely appointed rooms with period details. Whether you choose a king, double queen or a luxurious suite—all our rooms feature Serenity beds finished with Irish linens to give you all the comfort you need to reach your dreams.
Dine on a piece of history at the restaurant where a reinvented past collides with an innovative menu.
Raise your glass at this rooftop watering hole and pay homage to the most famous astronauts in Huntsville history.
106 JEFFERSON indulges planners and guests with a unique and memorable event experience. We also have professional event coordinators who specialize in weddings, so that you can partner with a group whose professionalism and attention to detail is unmatched. Located in the heart of downtown with easy access to the city’s cultural centers, eclectic shopping and nightlife.
The only lifestyle boutique hotel in downtown Huntsville, the 106 JEFFERSON serves as the heartbeat of the Space Capital of the country. The 106 JEFFERSON offers easy access to plenty of character-filled coffee shops, high-end boutiques, buzzed about restaurants and bars, impressive art galleries, and stately buildings where history’s been written. From our well-positioned perch, get all the comfort and charm of a residential neighborhood without sacrificing the conveniences of a well-connected urban locale.